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Focused Ultrasound vs Deep Brain Stimulation: Which Tremor Treatment Is Better?

It can be quite frustrating to live with severe tremors. Hand tremors can interfere with most day-to-day tasks like drinking tea, writing, typing, buttoning clothes, or even talking on the mobile phone. Not all medications will work for all people, and some patients might still experience major symptoms while on medication.

For people with severe essential tremor and also for patients with tremor-related Parkinson’s disease, some of the advanced treatment options will be considered. Two of the treatment options that have been the subject of most discussions and debate in the current times are Deep Brain Stimulation (DBS) and MR-guided Focused Ultrasound (MRgFUS).

As is apparent, both these treatment options work towards improving the quality of life of the patients by reducing the tremors. However, they go about in completely different ways. Patients can get a better understanding of both the treatment options in terms of their effectiveness, safety, and suitability in the particular case, to make a more informed decision while consulting their neurologist.

What are tremors?

Tremors are rhythmic shaking movements that are involuntary. They mostly affect the hands, but can also affect the arms, head, voice and legs.

In some cases, they can occur while holding objects, while others can experience tremors while at rest.

Tremors are classified based on their severity and the level of damage they inflict on the activities of everyday life.

Disorders that are often associated with tremors

1) Essential Tremor (ET)

Essential tremor is a condition that causes the most prevalent shaking in most people. It is mostly manifested when a person is engaged in activities that require writing, eating, or when an individual needs to hold an object.

2) Parkinson’s Disease (PD)

Tremors can also be brought on by Parkinson’s disease, and often occur when a person’s body is completely at rest. This condition is often accompanied by a variety of other symptoms, including stiffness, slowed body movement and loss of balance.

Tremor Symptoms

Those experiencing tremors can have symptoms including:

  • Inability to write neatly
  • Difficulty with the simple tasks of eating and drinking
  • Shaky hands during most tasks
  • Social anxiety
  • Less independence
  • Increased stress and anxiety

In the event medications do not suffice, options such as DBS or Focused Ultrasound are available and can be considered.

Diagnosing Tremor Disorder

Before treatment is started, there are several neurological assessments done.

History and Neuro Exam

An evaluation may include:

  • Pattern of tremors
  • Family medical history
  • Balance and coordination
  • Muscle pain and stiffness

Brain imaging

The use of MRIs may show things like structural issues of the brain, in order for a more focused treatment plan to be created.

How does Deep Brain Stimulation (DBS) Work?

Deep Brain Stimulation is an invasive treatment reserved for severe cases of tremors and movement disorders.

The process includes:

  • The insertion of many electrodes into the brain
  • A device similar to a pacemaker is placed in the subdermal area of the chest
  • The device sends electrical impulses to control abnormal brain activity linked to tremors

DBS is a common procedure that can be an extremely effective treatment in the long term.

Deep Brain Stimulating Device Advantages

Customized Treatment

One of the most notable benefits of the technology is that interventions to treat symptoms can be adapted to improve overall health.

Effectively Treats Both Sides of the Body

It is possible for Deep Brain Stimulation to effectively treat bilateral symptoms.

Long Lasting Control of Symptoms

The technology has helped many patients achieve a quality of life by significantly reducing tremors.

DBS is an invasive corrective measure that comes with various risks associated with almost all forms of surgery. These include, but are not limited to:

  • Infection of the surgical site
  • Bleeding in the brain
  • Complications from the device
  • Compromised speech and balance
  • Possibility of battery replacement in the future

Recovery can also be lengthy in comparison to other non-invasive treatment measures.

What Is MR-Guided Focused Ultrasound?

MR-Guided Focused Ultrasound utilizes precisely controlled waves to minimize the treatment area. MR-based temperature mapping gives the physician the precision to eliminate the area with disruptive brain signals without cutting.

Advantages of Focused Ultrasound

No Surgical Incisions

Implanting devices or opening the skull is not a requirement in Focused Ultrasound.

Faster Recovery

An absence of wounds makes recovery faster.

Improvement in Tremors

Notable improvement in tremors is experienced during or shortly after treatment.

No Maintenance

There is no implanted battery or device that will require maintenance.

Risks of Focused Ultrasound

Even though the treatment is generally safe, it still comes with the possibility of some of the following effects:

  • Temporary numbness
  • Balance difficulties
  • Tingling
  • Mild headaches
  • Problems associated with walking

DBS comes with a treatment that is adjustable and reversible; Focused Ultrasound does not offer the same after treatment.

Which Treatment Is Better?

Every treatment must be assessed on a patient-by-patient basis. The best treatment will always be attributed to the patient’s particular condition, age, health, and the severity of their symptoms.

DBS is Better for Patients Who are:

  • Younger
  • Have tremors on both sides of the body
  • Need an adjustable treatment for an extended time
  • Have Parkinson’s disease with multiple motor symptoms

Focused Ultrasound is Better for Patients Who:

  • Want a treatment that is non-invasive
  • Are older and unable to tolerate a large operation
  • Want a treatment with a faster recovery time
  • Have tremors that are mainly on one side of the body

A neurologist and neurosurgeon assess each case and choose the most appropriate procedure.

Recovery For Each Treatment

Recovery From DBS

It may last a few weeks. Patients need additional hospital visits to have the device settings adjusted to their liking for symptom improvement.

Recovery From Focused Ultrasound

Most people are able to go home one to two days after treatment.

Do These Treatments Provide a Cure?

Neither of the two methods fully cures essential tremor nor Parkinson’s disease. DBS and Focused Ultrasound are able to alleviate symptoms and help with the overall quality of life.

Final Thoughts

Severe tremors can impact a person’s quality of life and make people lose their confidence and even their ability to care for themselves. For those patients where the usual prescribed medication has not provided adequate symptom relief, other treatment modalities such as DBS and MR-guided Focused Ultrasound can provide a major improvement.

DBS can control symptoms for long periods of time, and it can be adjusted; however, it is a surgical procedure, and devices will be implanted into the body. On the other hand, Focused Ultrasound does provide a treatment option that is faster to recover from and is non-invasive, but it does not control symptoms for long periods of time, and it cannot be adjusted.

It is essential that the risks of either treatment are carefully weighed and evaluated both with a neurologist and the experienced team to help with the decision.

Questions and Answers

1. Is Focused Ultrasound less risky than Deep Brain Stimulation?
Neither Focused Ultrasound nor DBS is completely without risks when they are performed, but Focused Ultrasound is less invasive than DBS since no surgical cuts are required.

2. After treatment, can tremors come back?
DBS and Focused Ultrasound can provide long-term relief for tremors. However, the symptoms can continue to advance over the years based on the condition.

3. Which treatment has a quicker recovery?
Focused Ultrasound has a significantly shorter recovery period than the Deep Brain Stimulation surgery.

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